About the Lab.
The Laboratory of Experimental Medicine is located on the new campus of the John A. Burns School of Medicine, close to downtown Honolulu right by the ocean.
The main campus of the University of Hawaii at Manoa, a Class 1 Research University with 20,000 students, is four miles northeast and houses many of our collaborating colleagues.
Researchers in the lab are focused in three main disease areas.
Heart failure
Diabetes and metabolic syndrome
Cancer immunology
We are specifically in the ion channels that regulate these disease.
We use a large range of techniques including extensive biochemical, molecular and in vivo tools.
About the Principal Investigator (PI).
Principal Investigator is a phrase used to describe the "head of the laboratory" or "research group leader".
Dr. Alexander Stokes is the PI of the Laboratory of Experimental Medicine, and Assistant Professor in Department Cell & Molecular Biology, John A. Burns School of Medicine.
He is also the former (2013-19) Director of the Hawai'i Biorepository, a member of the UH Hawai'i Data Science Institute, and is a faculty member at Chaminade University in their Biology, Data Science and MBA programs
Originating from the UK, Dr. Stokes has an impeccable pedigree from twenty years of experience in research and development. He has an excellent track record of cutting edge research that was established at world-class European and U.S. institutions including Genzyme, Britain's Imperial Cancer Research Fund and Harvard Medical School; and he has published in leading journals. In 2000 Dr. Stokes moved to Queens Medical Center, Honolulu HI, and in 2008 he moved to the John A. Burns School of Medicine, University of Hawaii. He has been consistently funded by NIH (INBRE, BRIC and COBRE grants), and foundations such as Hawai'i Community Foundation since joining JABSOM. He is also a collaborator on grants from the Air Force Research Laboratories and NSF. Dr. Stokes’ current interest areas are:
HEART FAILURE
DIABETES AND METABOLIC SYNDROME
CANCER THERAPIES
DATA ANALYTICS
ENTREPRENEURSHIP
Dr. Stokes recognized that leveraging the tremendous pharmaceutical potential of TRP channels relied on the development of sophisticated in vivo models for their role in human pathology. His approaches and findings transformed the ion channel TRVP1 from a minor target in analgesia to a major player in the billion-dollar cardiovascular market space, and offers real hope to millions of patients afflicted by heart failure. He is also working on ion channels in cancer and diabetes with a similar focus on developing these attractive therapeutic targets into robust therapies that change and save lives.
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Funding
As well as research funding in the form of grants, donations have already helped us to successfully develop the lab, and its research, in an effort toward improving the health of the country and the state of Hawaii.
There are ways you can support our ongoing efforts.
You can support research on specific diseases, or support a student, or post doctoral fellow, in the lab. Donated funds can be used for anything from pipette tips to stipends.
If you are interested in a monetary donation, the laboratory has a specific fund that is maintained by the UH Foundation. You may download their pledge form here.
Our fund details are as follows:
125-2890-4 • Molecular Disease Research • Department of Cellular and Molecular Biology
For more information on how you can help, please feel free to contact us by
Location
Laboratory of Experimental Medicine
Department of Cell & Molecular Biology John A. Burns School of Medicine
Biosciences Building 222
651 Ilalo Street
Honolulu, HI 96813 USA